Lydon, 63, also known by his stage name Johnny Rotten, said he was good friends with the rave icon, 49, who was found hanged on Monday.
Speaking to TMZ at the premiere of the 'Punk' docuseries at Hollywood's SIR Studios, Lydon said Flint’s death should serve as a “wake-up call” to the music industry.
"My heart is broken for him. He was a good friend of mine. Don't get me wrong but nobody loved him and he was left alone and he got destroyed," Lydon said.
He said struggling performers should look out for each other more in the music industry.
"Why? Why do so many people in this industry be left alone? Come to me, I'm Johnny,” he said.
"What you got to understand is we are not looking after each other anymore and we should.
"Any of you out there need help, come talk to me. We do not need to die."
It comes after The Sun spoke to pals who claimed Flint begged his estranged wife Mayumi Kai to come home days before he died.
He was found dead at their Essex farmhouse which had just gone on the market.
He is said to have delayed selling it as he had hoped for a reconciliation with Mayumi, 31, after splitting last year.
A source said: “Keith always hoped they could make it work and he made various phone calls to her, pleading with her.
“But she didn’t change her mind and insisted they sell the house. It broke Keith. Mayumi isn’t to blame but it seems that Keith didn’t think he could carry on without her.”
An employee is believed to have found Keith’s body at the £1.5million marital home in Dunmow, Essex. He ran 5k in Chelmsford on Saturday morning but pals feared he had slipped back to his hedonistic ways.
Footage also emerged showing him appearing to black out before being held up by security guards at the Prodigy’s last-known UK gig in Brighton last November.
Fan Kenneth Edwards, 52, said it looked like he was “on some sort of drugs”, adding: “I’ve been to a lot of his concerts and not seen that before. It was shocking to see.”
Blunt's hug tears
TEARFUL James Blunt revealed Keith Flint once gave him a hug at the Q Awards after he was snubbed by other stars including Damon Albarn and Noel Gallagher.
He tweeted yesterday: “In our business, there are no prizes for being kind, but if there was, that Grammy would be yours.”
If you, or anyone you know, needs help dealing with mental health problems the Samaritans can be contacted on 116 123, or visit Mind’s website.
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